What are the possible side effects of Prazine 25mg?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stuffy nose.
- Feeling sleepy.
- Dizziness.
- Headache.
- Upset stomach.
- Dry mouth.
- Constipation.
- Feeling nervous and excitable.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
See also:
Prazine 25mg side effects (in more detail)
Side effects of Prazine 25mg in details
Prazine 25mg is a member of the phenothiazine group of drugs and the side effects associated with that group have been noted. These include drowsiness, sedation, dry mouth, nasal stuffiness. Other possible anticholinergic side effects are blurred vision, tachycardia, constipation and urinary hesitancy or retention when due to enlarged prostate.
Confusional states or epileptic fits can occur. Extrapyramidal symptoms and hyperpyrexia have been reported. Neuroleptic malignant syndrome (hyperthermia, rigidity, autonomic dysfunction and altered consciousness) may occur with any neuroleptic.
Sexual function may be impaired. Agranulocytosis and transient leucopenia have rarely been reported. Allergic skin reactions and photosensitivity have also been reported.
Prazine 25mg rarely causes obstructive jaundice associated with stasis in biliary canaliculi. Prazine 25mg treatment should then be withdrawn and not given again. Transient abnormalities of liver function tests may occur without jaundice.
Some individuals may be susceptible to the drug in low dosage and show paradoxical effects of excitement, agitation or insomnia and other minor side effects. The elderly are particularly susceptible to side effects of Prazine 25mg, especially to the sedative, hypotensive and temperature regulation effects. These effects may be dose related.
Withdrawal symptoms, including nausea, vomiting, sweating, insomnia, recurrence of psychotic symptoms and involuntary movement disorders have been noted.
Phenothiazines can produce ECG changes with prolongation of QT interval and T-wave changes, ventricular arrhythmias (VF, VT (rare)), sudden unexplained death, cardiac arrest and Torsades de pointes have been reported
Cases of venous thromboembolism, including cases of pulmonary embolism and cases of deep vein thrombosis have been reported with antipsychotic drugs – Frequency unknown
Prazine 25mg contraindications
Use in patients hypersensitive to the active ingredient or other phenothiazines.
Use in patients in coma
Use in patients with bone marrow depression
Use in patients with phaeochromocytoma
Use during lactation
Do not use during pregnancy, especially during the first three months, unless there are compelling reasons.
References
- DTP/NCI. "promazine: The NCI Development Therapeutics Program (DTP) provides services and resources to the academic and private-sector research communities worldwide to facilitate the discovery and development of new cancer therapeutic agents.". https://dtp.cancer.gov/dtpstandard/s... (accessed September 17, 2018).
- European Chemicals Agency - ECHA. "Promazine: The information provided here is aggregated from the "Notified classification and labelling" from ECHA's C&L Inventory. ". https://echa.europa.eu/information-o... (accessed September 17, 2018).
- HSDB. "PROMAZINE". https://toxnet.nlm.nih.gov/cgi-bin/s... (accessed September 17, 2018).
Reviews
The results of a survey conducted on ndrugs.com for Prazine 25mg are given in detail below. The results of the survey conducted are based on the impressions and views of the website users and consumers taking Prazine 25mg. We implore you to kindly base your medical condition or therapeutic choices on the result or test conducted by a physician or licensed medical practitioners.User reports
Consumer reported side effects
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Information checked by Dr. Sachin Kumar, MD Pharmacology
